Under Microscope

O Prêmio da Fundação Shoman No dia 28/12/2020, o prêmio da fundação Shoman foi concedido a 447 cientistas árabes, devido às suas produções científicas durante últimos cinco anos, as (os) cientistas foram selecionados entre 5032 candidatos.     O prêmio é uma ideia para agradecer as (os) cientistas pela força e pela dedicação, aqueles que não querem saber de férias e de festas, favorecendo os livros e os laboratórios em que a sua felicidade esteja em ter um progresso científico.   A fundação Shoman apoia a pesquisa científica e as (os) cientistas árabes, as suas atividades começaram em 1978 e está continuando.     Eu gostaria de parabenizar os nossas (os) professoras (es) pelo prêmio e desejar mais sucesso e progresso para todos.     Link: https://youtu.be/JTN8sxhJc60   Wasim Al Shebli em 29/01/2020

A pesquisa na área de medicina veterinária Hoje 25/12/2020; assisti uma entrevista com o Prof.Dr. Islam Mohamed Saadeldin (em árabe), sobre as pesquisas na área de medicina veterinária com foco nos pontos seguinte; Clonagem: a ideia de clonagem e seu recrutamento na prática tal como a clonagem de cavalos e na pesquisa tal como a clonagem terapêutica; um ponto interessante que foi dito é a origem das mitocôndrias ;   Partenogênese: o que é a partenogênese e o seu recrutamento especialmente, para obter células de tronco , umas pesquisas bem interessantes foram sobre a transferência de embriões partenogenético para receptoras e o desenvolvimento destes embriões até 31 dias da gestação em cão;   Carne in vitro : a importância desta técnica e os desafios;     Edição genética: os métodos da edição genética e seu recrutamento no melhoramento genético em vacas de leite na produção e resistência térmica; foram ditos os trabalhos do Prof.Dr. Peter Hansen (Universidade de Florida) sobre as

Ovarian Cyst Ovarian cyst is an abnormal follicular structure that forms due to ovulation failure, reaching larger diameter than ovarian follicle and persists for ≥10 days. This structure may regress spontaneously, stay permanently or be luteinized (Ball & Peter, 2004; Noakes et al., 2018), (Figure. 1). Ovarian cyst is more common in dairy than beef cows, especially in high milk production cows. It often occurs during the postpartum period (Hafez & Hafez, 2000; Noakes et al., 2018, Peter et al., 2009). Peter et al. (2018) consider the ovarian cyst as a development of anestrous case of persistence structures of dominant follicles, but Noakes et al. (2018) do not consider the importance of CL absence in this case. The failure in luteinizing hormone (LH) releasing mechanism is the most evident cause of ovarian cyst which is not related to deficiency in Gonadotropin-releasing hormone (GnRH) but it is related to low sensitivity of hypothalamic-pituitary axis to elevated secretion of

Effects of EPA on bovine oocytes matured in vitro with antioxidants: Impact on the lipid content of oocytes and early embryo development In this work ( Nikoloff et al., 2020), the effect of an unsaturated fatty acid (EPA) on lipids accumulation and distribution, cumulus  cumulus cells expansion, nuclear maturation, and ROS production in bovine  cumulus -oocyte complexes (COCs) was studies, as well as enhancing the oocyte competence by antioxidants; the most amazing section in this article is the methods, Nikoloff, N., Campagna, A., Luchetti, C., Carranza-Martín, A. C., Pascua, A. M., Anchordoquy, J. M., ... & Furnus, C. C. (2020). Effects of EPA on bovine oocytes matured in vitro with antioxidants: Impact on the lipid content of oocytes and early embryo development.  Theriogenology ,  146 , 152-161.  Link:  https://doi.org/10.1016/j.theriogenology.2019.11.028 Please read and leave your comment, Best Regards,   

  Oxidative and endoplasmic reticulum stress defense mechanisms of bovine granulosa cells exposed to heat stress   In this work (Alemu et al., 2018), the heat stress (HS)-Exposure time effect on  bovine granulosa cells were studied. T he reactive oxygen species (ROS) production and  BAX , CAT ,  PRDX1   genes expressions were changed according to exposure time (24 or 48 h); this work showed the amazing idea of HS-Exposure time effect on the cells, Alemu, T. W., Pandey, H. O., Wondim, D. S., Gebremedhn, S., Neuhof, C., Tholen, E., ... & Tesfaye, D. (2018). Oxidative and endoplasmic reticulum stress defense mechanisms of bovine granulosa cells exposed to heat stress.  Theriogenology ,  110 , 130-141.   Link:  https://doi.org/10.1016/j.theriogenology.2017.12.042   Please read and leave your comment, Best Regards, 

  Alteration of chemokine production in bovine endometrial epithelial and stromal cells under heat stress conditions In this work (Sakai et al., 2020), studied the effect  of heat stress (HS) on  chemokine production in endometrial epithelial and stromal cells, the effect of HS on these cell types is interesting to study; the experimental design of this work is an example to follow,   Sakai, S., Hatabu, T., Yamamoto, Y., & Kimura, K. (2020). Alteration of chemokine production in bovine endometrial epithelial and stromal cells under heat stress conditions.  Physiological Reports ,  8 (22), e14640.    Link: 10.14814/phy2.14640   Please, read and leave your comment, Best Regards,     

High doses of FSH induce autophagy in bovine ovarian granulosa cells     In this wrok ( Xiaorong et al., 2020)  the effect of different follicle stimulating hormone (FSH) doses on in vitro granulosa cells (GCs) and the pathways that mediate the FSH effect were studies; one of the creative ideas that I have found in this work is the detection of Autophagic vesicle, the autophagy ( a programmed cell death) is an interesting topic to study.   Xiaorong, T., Ma, L., Guo, S., Liang, M., & Jiang, Z. (2020). High doses of FSH induce autophagy in bovine ovarian granulosa cells via the AKT/mTOR pathway.  Reproduction in Domestic Animals .    Link: https://doi.org/10.1111/rda.13869    Please, read it and leave your comment, Best Regards, 

Analysis of bovine blastocysts indicates ovarian stimulation does not induce chromosome errors, nor discordance between inner-cell mass and trophectoderm lineages   This work (Tuttt et al., 2020) proved the role of in vitro maturation (IVM) in the chromosomal abnormalities in produced blastocysts. It is a interesting work.  Tutt, D. A. R., Silvestri, G., Serrano-Albal, M., Simmons, R. J., Kwong, W. Y., Guven-Ates, G., ... & Griffin, D. K. (2020). Analysis of bovine blastocysts indicates ovarian stimulation does not induce chromosome errors, nor discordance between inner-cell mass and trophectoderm lineages.  Theriogenology . Link:  https://doi.org/10.1016/j.theriogenology.2020.11.021 Please, read it and leave you comment. Best Regards;

  Heat Stress in Dairy Cattle Heat stress (HS) causes losses in dairy production and affects reproduction negatively, What do you know about HS in your area ?  How can we overcome HS ? How can we study  HS effect on the gametes ? Please, share your op inion and your personal and academic experiences! Comment under this post! Also, you can comment in Instagram and Twitter. Ten days later, the comments will be posted as a new post in this blog. You can write in Arabic, English or Portuguese! Obs. Use, APA style for citation (Google Scholar and https://owl.purdue.edu/owl/research_and_citation/apa_style/apa_formatting_and_style_guide/in_text_citations_author_authors.html for in text citation). Best Regards,  

 Under Microscope This blog represents views about scientific works especially the ones that focus on animal gametes and reproduction, the main objective is to discuss the views and thoughts with other scientists and specialists in the scientific areas, this blog can only progress with your collaboration. Best Regards, Wasim